cancer diagnosis

By Targets:	ADC Linker (2) Apoptosis (1) Biochemical Assay Reagents (1) Endogenous Metabolite (1) Fluorescent Dye (2) Pyroptosis (1) Pyruvate Kinase (1) Reactive Oxygen Species (1)
By Research Areas:	Cancer (12) Inflammation/Immunology (1)

Targets Recommended: BCRP

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116972

Etanidazole

SR 2508
Others Cancer

Etanidazole (SR 2508), a 2-nitroimidazole compound, is a hypoxic radiosensitizer used in cancer diagnosis and chemotherapy research .

Etanidazole SR 2508	Others	Cancer
Etanidazole (SR 2508), a 2-nitroimidazole compound, is a hypoxic radiosensitizer used in cancer diagnosis and chemotherapy research .

HY-D1456

TEPC466	Pyruvate Kinase	Cancer
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .

HY-129371

SPDV

ADC Linker Cancer

SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

SPDV	ADC Linker	Cancer
SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

HY-118774

Propofol β-D-glucuronide	Endogenous Metabolite	Inflammation/Immunology
Propofol β-D-glucuronide is a metabolite of Propofol sulfate and can be used for diagnosis to distinguish colorectal cancer from healthy individuals .

HY-129374

SPDH

ADC Linker Cancer

SPDH is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

SPDH	ADC Linker	Cancer
SPDH is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas.

HY-160063

SW1 aptamer sodium	Others	Cancer
SW1 aptamer sodium is a high-affinity DNA aptamer (Kd: 123.62 nM) that targets liver cancer SMMC-7721 cells and targets intracellular components within the nucleus. SW1 aptamer sodium can also identify various other types of cancer cells and tissues, serving as an effective molecular probe for clinical cancer diagnosis .

HY-134990

Hematoporphyrin monomethyl ether 1 Publications Verification	Apoptosis	Cancer
Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and research of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma .

HY-D1711

MHI-148	Fluorescent Dye	Cancer
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and research. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells .

HY-155486

HCy-AAN-Bio	Others	Cancer
HCy-AAN-Bio is a tumor-targeted hemicyanine (HCy) probe for Fluorescent/photoacoustic (FL/PA) imaging of legumain in vivo. Legumain can specifically cleave HCy-AAN-Bio with the generation of FL/PA signal. HCy-AAN-Bio is a powerful tool for early diagnosis of associated cancer .

HY-D1468

Phototherapeutic agent-1	Reactive Oxygen Species	Cancer
Phototherapeutic agent-1 is a multi-modal light diagnosis agent with aggregation-induced emission properties. have certain Phototherapeutic agent-1 has certain reactive oxygen species (ROS) generation capacity in illumination condition. Phototherapeutic agent-1 can effectively kill cancer cells and tumor tissue .

HY-W127805

Pentacarboxylporphyrin I dihydrochloride	Biochemical Assay Reagents	Others
Pentacarboxylporphyrin I dihydrochloride is an organic compound belonging to the family of porphyrin derivatives. It is commonly used in biochemical research as a reference standard for the quantification of porphyrins and related compounds in biological samples. Pentacarboxylporphyrin I dihydrochloride has several applications in the diagnosis and monitoring of porphyrias, a group of inherited disorders characterized by abnormalities in heme metabolism. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

HY-150971

ICy-Q	Pyroptosis	Cancer
ICy-Q is a quinone oxidoreductase 1 (NQO-1)-activated near-infrared (NIR) reagent which can react with NQO-1 to release the reduction product ICy-OH. ICy-OH selectively induces pancreatic cancer cell death through the pyroptosis pathway. ICy-Q can be used as an effective tool for rapid and accurate diagnosis of intraoperative pathological sections .

HY-149203A

MQA-P TFA	Fluorescent Dye	Others
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe that simultaneously detects ONOO ^-, viscosity, and polarity within mitochondria. MQA-P exhibits significant response to ONOO ^-, λ_em=645 nm; and NIR channel at λ_em>704 nm Medium is highly sensitive to viscosity/polarity. MQA-P possesses excited-state intramolecular charge transfer (ESICT) properties that are highly sensitive to polarity by designing the N,N-dimethylamino group as the electron donor and the quinoline cation unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .

Cat. No.	Product Name

HY-L072

Exosomes Compound Library	46 compounds
Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining. The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 46 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Exosomes Compound Library

46 compounds

Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Exosomes contain nucleic acids, proteins, lipids, amino acids, and metabolites, etc. Their diverse constituents can reflect their cell of origin. Exosomes are associated with immune responses, viral pathogenicity, pregnancy, cardiovascular diseases, central nervous system-related diseases, and cancer progression. Proteins, metabolites, and nucleic acids delivered by exosomes into recipient cells effectively alter their biological response. Such exosome-mediated responses can be disease promoting or restraining.

The biology of exosomes in disease is still emerging, and the number of studies addressing their utility in the diagnosis and treatment of various pathologies has increased substantially. MCE supplies a unique collection of 46 compounds with the activity of inhibiting or stimulating exsomes secretion/biosynthesis. MCE Exosomes Compound Library is a useful tool for exsomes research.

Cat. No.	Product Name	Type

HY-D1456

TEPC466	Fluorescent Dyes/Probes
TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .

TEPC466

Fluorescent Dyes/Probes

TEPC466 is a novel TEPP-46-based aggregation-induced emission (AIE) probe. TEPC466 shows a high degree of selectivity and sensitivity for the detection of PKM2 protein via the AIE effect. EPC466 can be used for the detection of PKM2. TEPC466 is successfully applied in imaging the PKM2 protein in colorectal cancer cells with low toxicity. TEPC466 is a useful tool for cancer diagnosis and research .

HY-149203

MQA-P	Fluorescent Dyes/Probes
MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO ^-, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO ^- (λ_em=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λ_em>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .

MQA-P

Fluorescent Dyes/Probes

MQA-P is a multifunctional near-infrared (NIR) fluorescent probe for simultaneously detecting ONOO ^-, viscosity, and polarity within mitochondria. MQA-P exhibits a remarkable turn-on response to ONOO ^- (λ_em=645 nm) and is highly sensitive to viscosity/polarity in the NIR channel with λ_em>704 nm. MQA-P exhibits excited-state intramolecular charge transfer (ESICT) feature that is highly polarity-sensitive by engineering N,N-dimethylamino as the electron donor and a quinoline cationic unit as the electron acceptor. MQA-P is used for ferroptosis or cancer diagnosis in vitro and in vivo via dual-channel images .

Cat. No.	Product Name	Type

HY-W127805

Pentacarboxylporphyrin I dihydrochloride	Biochemical Assay Reagents
Pentacarboxylporphyrin I dihydrochloride is an organic compound belonging to the family of porphyrin derivatives. It is commonly used in biochemical research as a reference standard for the quantification of porphyrins and related compounds in biological samples. Pentacarboxylporphyrin I dihydrochloride has several applications in the diagnosis and monitoring of porphyrias, a group of inherited disorders characterized by abnormalities in heme metabolism. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

Pentacarboxylporphyrin I dihydrochloride

Biochemical Assay Reagents

Pentacarboxylporphyrin I dihydrochloride is an organic compound belonging to the family of porphyrin derivatives. It is commonly used in biochemical research as a reference standard for the quantification of porphyrins and related compounds in biological samples. Pentacarboxylporphyrin I dihydrochloride has several applications in the diagnosis and monitoring of porphyrias, a group of inherited disorders characterized by abnormalities in heme metabolism. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

Cat. No.	Product Name	Target	Research Area

HY-106033

Edotreotide DOTATOC; SDZ-SMT 487; SMT 487	Peptides	Cancer
Edotreotide is a somatostatin analogue. Edotreotide bound to various radionuclides, has the potential for the research and diagnosis of certain types of cancer .

Cat. No.	Product Name	Target	Research Area

HY-P99834

Crefmirlimab 89Zr-Df-IAB22M2C	Inhibitory Antibodies	Cancer
Crefmirlimab (89Zr-Df-IAB22M2C) is an anti-human CD8 probe targeting CD8 antigen, which can be used in the diagnosis of various cancers .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-118774

Propofol β-D-glucuronide	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
Propofol β-D-glucuronide is a metabolite of Propofol sulfate and can be used for diagnosis to distinguish colorectal cancer from healthy individuals .

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cancer diagnosis

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Fluorescent Dye

Biochemical Assay Reagents

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